Extended Data Figure: Spine Density
Analysis of spine density of medium spiny neurons in the ventral striatum from adult CON and MIA mice.
Load and subset data
## # A tibble: 2 × 3
## Group mouse cells
## <chr> <int> <int>
## 1 CON 6 28
## 2 MIA 7 34Plot data
Perform t-test between control and MIA
## [,1]
## Con Normality 0.549
## MIA Normality 0.426## Data is normal, use t-test##
## Welch Two Sample t-test
##
## data: data2$density by data2$Group
## t = -0.6, df = 11, p-value = 0.6
## alternative hypothesis: true difference in means between group CON and group MIA is not equal to 0
## 95 percent confidence interval:
## -0.237 0.140
## sample estimates:
## mean in group CON mean in group MIA
## 1.19 1.23Conclusion - Ventral striatum MSNs have a normal spine density.
Reproducibility info
## [1] "2022-07-02 17:33:55 EDT"## ─ Session info ───────────────────────────────────────────────────────────────
## setting value
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## date 2022-07-02
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